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KMID : 0381019850180010023
Korean Journal of Nutrition
1985 Volume.18 No. 1 p.23 ~ p.28
Effect of Maternal Dietary Restriction on Serotonin and Catecholamine Levels of the Developing Rat Brain
Chang Kyung-Ja

Choi Haymie
Abstract
A quantitative restriction of maternal diet was given to the Sprague Dawley rats during the third week of gestation and during the lactation. Dams of deficient groups were fed 20g of a stock diet a day and compared with the control group fed ad libitum throughout the experimental period Dietary restriction started from birth in deficient 1 group and from the 14th day of gestation in deficient 2 group. Brain serotonin, norepinephrine, dopamine, and tyrosine of offsprings were determined at several intervals. Brain serotonin of offsprings of deficient groups 1 and 2 were significantly lower than the control and significant differences between the deficient groups were noticed. Brain catecholamines and tyrosine of offsprings of deficient groups were significantly lower than the control and there was no difference between the deficient groups. Maternal dietary restriction during the gestation and the lactation may have retarded the synthesis of serotonin and catecholamines in the brain.
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